NeuExcell's ATN ASTROCYTES TO NEURONS^TM Platform aims at disrupting the dogma that neurons are irreplaceable.

The dogma of neuroregeneration has been that neurons cannot be repaired or replaced.  NeuExcell's innovative technology challenges that doctrine and focuses on regenerating neural tissue.  While neurons cannot divide to regenerate themselves, glial cells are a renewable source for generating neurons at the site of injury.  Our ATN ASTROCYTES TO NEURONS^TM platform uses gene therapy to deliver specific transcription factors to glial cells in the brain, which converts these cells into functional and fully integrated neurons. We have generated proof of concept in rodents as well as in NHP with robust pre-clinical data for 3 lead indications, glioblastoma (GBM), stroke, and Alzhermer's Disease (AD).